Medicinal and chemical aspects of Tetrazoles: an overview

Abstract

Various synthetic organic heterocyclic compounds including Tetrazoles have been reported to have many biological activities like analgesic, anti-inflammation, antimicrobial, anticancer, antidiabetic and others. Therefore, tetrazoles are the molecules having diverse activity and the potential role in biosciences. Moreover, lot many things to be explored about these versatile compounds. It has been known those tetrazole derivatives as ligands in coordination chemistry, as surrogate molecule for carboxylic acid and their resistance to metabolically biological degradation mechanism; mostly it can be used as for synthesising new drug especially anticancer molecules. This review highlights the important things about the potential possible role of terazole and summarizes the reactions and biological activity of Tetrazoles.