The use of H4IIE Cells to Detect the Polychlorinated Biphenyls in House Dust

Abstract

In the present study, settled house dust samples were collected form Pearl River Delta, China for PCBs analyses. Total PCBs concentrations in house dust ranged from 50.9 to 1066 ng/g, with a median of 181 ng/g. PCB77, 114, 118, 157, 153, and 194 were found as the dominant congeners. TEQbio of all dust samples derived from biological assays ranged from 56.7 to 865 pg TEQ/g, which was mostly contributed (average 54.6%) by TEQPCB derived from chemical analyses. In addition, a significant correlation was obtained between TEQPCB and TEQbio (r = 0.89, p< 0.01, n=23). These results suggested that dioxin-like PCBs may be the dominant AhR agonists contained in the dust samples. Risk assessment indicated that indoor dust is an important environmental medium of children exposure to dioxin-like PCBs.