Pharmacotherapy of Paediatric ADHD: Challenges and Emerging Alternatives

Abstract

Attention-Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder in children, characterized by inattention, hyperactivity, and impulsivity. Pharmacotherapy, primarily with stimulants like methylphenidate and amphetamines, is effective but often limited by side effects and variability in response. This review explores current pharmacological treatments, emerging alternatives, and the role of behavioral interventions in optimizing therapeutic outcomes. Personalized approaches, including pharmacogenetics, may improve efficacy and reduce adverse effects, highlighting the need for continued research into innovative ADHD management strategies.