Rutin phytosomes- For treatment of arthritis

Abstract

Phytosomes are advanced forms of herbal products that are better absorbed and utilized by the body, and consequently produce better results than conventional herbal extracts. Phytosomes are produced via a patented process whereby the individual components of an herbal extract are bound to phosphatidylcholine—an emulsifying compound derived from soy. Phosphatidylcholine is also one of the chief components of the membranes in our cells. The objective of the present study was to formulate phyto-phospholipid complexes (phytosomes) of Rutin and to evaluate the feasibility for its potential transdermal application in inflammatory conditions for sustained therapeutic benefits. Further Rutin phospholipid complex may be considered as a promising drug delivery system for improving the overall oral absorption and bioavailability of Rutin. . Rutin as colloidal carrier enhanced the drug penetration into the skin, and because of its lipoidal nature, the penetrated drug concentrates in the skin and remains localized for a longer period of time, thus enabling drug targeting to the skin.